Vaccine- who will have it?

[Banker]

1 hour ago, Neil Down said:

He can feck off if he thinks I'm waiting 10 years for that release...

It will be commercially sensitive 

[dilligaf]

2 hours ago, Neil Down said:

He can feck off if he thinks I'm waiting 10 years for that release...

Have you been in hiding ?

[Newbie]

12 hours ago, madmanxpilot said:

This makes interesting reading. Lots of hot topics covered by the Astra Zeneca CEO. 

https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/amp/?__twitter_impression=true

Interesting that he says he thinks the one dose strategy followed by the UK is the right way to go, at least for the AZ vaccine.

[piebaps]

I for one don't want to see Ashie's big release.

[madmanxpilot]

2 hours ago, Newbie said:

Interesting that he says he thinks the one dose strategy followed by the UK is the right way to go, at least for the AZ vaccine.

Indeed. Oxford/AZ have said that there is a 'sweet spot' for administering the second dose between eight and twelve weeks. This may explain why the half dose/full dose regimen showed greater efficacy as this sub group had their doses administered at a greater interval.

 

As this is the case, I'm unsure why they haven't changed the recommended dosing schedule with the regulators.

 

Prof Wei Shen Lim, the chair of the Covid-19 immunisation group of the JCVI, told MPs further analysis by AstraZeneca showed the improved protection came from spacing out the doses.

“People who had the half dose then full dose were those who were vaccinated at a longer time interval, roughly six to 12 weeks, and what they’ve seen in their data is that people who have the second dose later probably have a three times higher antibody level than those who were vaccinated earlier. So if anything, it suggests that increasing the dose interval is beneficial,” he said.

Sir Mene Pangalos, the executive vice-president of biopharmaceuticals research and development at AstraZeneca, told the committee the first vaccine shot was more protective over time.

“What we’re seeing with our data so far is that as you go to the eight- to 12-week interval, you actually increase vaccine efficacy. People are protected enough with the first dose, to around 70%, but we see that within that eight- to 12-week interval is actually the sweet spot,” he said.

[Banker]

36 minutes ago, madmanxpilot said:

Indeed. Oxford/AZ have said that there is a 'sweet spot' for administering the second dose between eight and twelve weeks. This may explain why the half dose/full dose regimen showed greater efficacy as this sub group had their doses administered at a greater interval.

 

As this is the case, I'm unsure why they haven't changed the recommended dosing schedule with the regulators.

 

Prof Wei Shen Lim, the chair of the Covid-19 immunisation group of the JCVI, told MPs further analysis by AstraZeneca showed the improved protection came from spacing out the doses.

“People who had the half dose then full dose were those who were vaccinated at a longer time interval, roughly six to 12 weeks, and what they’ve seen in their data is that people who have the second dose later probably have a three times higher antibody level than those who were vaccinated earlier. So if anything, it suggests that increasing the dose interval is beneficial,” he said.

Sir Mene Pangalos, the executive vice-president of biopharmaceuticals research and development at AstraZeneca, told the committee the first vaccine shot was more protective over time.

“What we’re seeing with our data so far is that as you go to the eight- to 12-week interval, you actually increase vaccine efficacy. People are protected enough with the first dose, to around 70%, but we see that within that eight- to 12-week interval is actually the sweet spot,” he said.

Don’t worry, Ashie has decided our doses!!

[madmanxpilot]

52 minutes ago, Banker said:

Don’t worry, Ashie has decided our doses!!

It was quite revealing when at one of the briefings last week he spent quite a while explaining how the IOM's clinicians had debated whether to extend the period between doses, and it was a consensus of opinion that led to the adherence of the 3 or 4 week gap. This despite him, on several occasions, saying that they had a legal obligation to comply with the dosing regime specified in the approval.

He has uttered many other specious comments that don't stand up to scrutiny. He was adamant that the vaccination appointments for the over 80s were not being done in alphabetical order - yet when the 111 operator was speaking  to my parents when they were making their appointment last week, she said they had been done that way.

I struggle to believe anything they say when it comes to technical matters. As Fauci said last week, 'if you don't know the answer, don't guess' - I think our leadership team could do with taking a leaf out of the good doctor's book.

Edited January 27, 2021 by madmanxpilot

[Banker]

16 minutes ago, madmanxpilot said:

It was quite revealing when at one of the briefings last week he spent quite a while explaining how the IOM's clinicians had debated whether to extend the period between doses, and it was a consensus of opinion that led to the adherence of the 3 or 4 week gap. This despite him, on several occasions, saying that they had a legal obligation to comply with the dosing regime specified in the approval.

He has uttered many other specious comments too that don't stand up to scrutiny. He was adamant that the vaccination appointments for the over 80s were not being done in alphabetical order - yet when the 111 operator was speaking  to my parents when they were making their appointment last week, she said they had been done that way.

I struggle to believe anything they say when it comes to technical matters. As Fauci said last week, 'if you don't know the answer, don't guess' - I think our leadership team could do with taking a leaf out of the good doctor's book.

Over 80s definitely in alphabetical order as my mum told the same, also no coordination as to where’s best to send them ie Ramsey people to airport, Colby to Douglas.

 He never answered questions as to why so few over 80s were vaccinated in first run of c4000 .

[madmanxpilot]

20 minutes ago, Banker said:

Over 80s definitely in alphabetical order as my mum told the same, also no coordination as to where’s best to send them ie Ramsey people to airport, Colby to Douglas.

 He never answered questions as to why so few over 80s were vaccinated in first run of c4000 .

If you look at the 'phase one cohorts' subsection of the vaccine dashboard that was made available recently https://covid19.gov.im/vacstats, only the over 80s, those resident or working within care homes or those working in healthcare have been vaccinated so far. These people represent  the first two groups of the priority list.

 

From that, I would deduce that there are far more workers in those two groups than over 80s.

 

Edited January 27, 2021 by madmanxpilot

[Roger Mexico]

It's a fun website to play about with and they've improved it even since yesterday[1]. But there were 4397 people aged 80+ in the last Census (2106) a number I suspect will only have increased.

But vaccinations for only 121 care home residents and 493 others in this group have currently given (I don't think any will have had their second dose yet).  So it's because they have prioritised staff rather than because there aren't the over-80s to be vaccinated.

 

[1]  Presumably someone pointed out that, fashionable though pastel shades are, white lettering on them isn't exactly readable.  It would nice to get rid of the US date formats though.

[Southernman]

5,365 vaccinations so far of which 724 were for over 80s.

[Nellie]

Airport hub up and running, but by 11.00am around 30 mins behind schedule and around 50-60 elderly folk constantly outside, in the queue to be allowed into the building. 

Not an auspicious start!

[Happier diner]

And some good news. No anticipation of reduced supply of AZ vaccine

 

https://www.bbc.co.uk/news/uk-55838272

 

[Beelzebub3]

Did I hear correctly on Manx radio news Mr Ashford, when asked how much the hubs cost he replied that he was unable to tell how much as they do not know yet! FFS that is a unbelievable for a Government official to admit they do not know, I believe questions need to be answered to the following issue's,

1 Was any sort of a tender undertaken?

2 Were all IOM contractors asked to price for the work?

3 Was "Due dilligance" used in the process and was the treasury procurement team involved?

4 As we knew 6 month's ago there was going to be a rollout of the vaccine were plan's in place to use hub's or otherwise what was in place?

5 Which contractor was used to complete the work and what specification and who issued the specific plans and under what recommendations?

I am confident that none of the questions above will be answered honestly.

[Two-lane]

41 minutes ago, Nellie said:

Airport hub up and running, but by 11.00am around 30 mins behind schedule and around 50-60 elderly folk constantly outside, in the queue to be allowed into the building. 

In a Manx Radio audio clip today Ashford says that the airport was specifically chosen because it has enough space for people to queue, without having to wait outside. Hmmm.

If there was a snowstorm or heavy rain today, the old fogeys would be dropping like flies. And did they provide folding chairs for the oldies to sit on like in some of the UK centres, or would that be an unreasonable cost.