Cambon Posted February 12, 2021 Share Posted February 12, 2021 54 minutes ago, Roger Mexico said: It's worth pointing out that the recommendations were always "two doses administered with an interval of between four and 12 weeks", so there's no change here. As I've said before looking at the trial data I'm not as convinced about increased protection as they are, but a longer gap would be in line with original recommendations and if infection rates are low there's probably less worry about a longer period with lower protection, even if protection isn't increased. The only arguments for having the tightest possible schedule are administrative with fear of the second dose being missed or late. This should be less of a problem in a smaller, less mobile place such as Guernsey unless the administration is incompetent and inflexible. The point of the tighter schedule is to get the maximum protection as quickly as possible for those most at risk. Once we get to vaccinating the under 50s, it is worth considering. Quote Link to comment Share on other sites More sharing options...
Happier diner Posted February 12, 2021 Share Posted February 12, 2021 9 minutes ago, Cambon said: The point of the tighter schedule is to get the maximum protection as quickly as possible for those most at risk. Once we get to vaccinating the under 50s, it is worth considering. That's fair enough, although if we get infections and they spread in an uncontrolled way, I would hope that the plan would be changed. Quote Link to comment Share on other sites More sharing options...
Newbie Posted February 12, 2021 Share Posted February 12, 2021 1 hour ago, Cambon said: The point of the tighter schedule is to get the maximum protection as quickly as possible for those most at risk. Once we get to vaccinating the under 50s, it is worth considering. It surely depends upon which vaccine is being administered. Those receiving the Pfizer vaccine in the earlier groups should get there second dose as specified after 3 weeks, but for those getting the AZ vaccine, the latest evidence shows that giving the second dose after a longer interval provides greater protection, hence the advice from WHO, SAGE and from the CEO of Astra Zeneca who supported the UK approach for their vaccine. As far as the AZ vaccine is concerned, there is no logic in saying that we want to give the second dose as early as possible to those most at risk (i.e. after 4 weeks), because we want to give them maximum protection as quickly as possible, if the science shows that doing so doesn't give the maximum protection. Ultimately that strategy would leave the highest priority groups with lower levels of protection than the lower priority groups (assuming that the dosing schedule was changed for those groups as you suggested). 1 Quote Link to comment Share on other sites More sharing options...
Cambon Posted February 12, 2021 Share Posted February 12, 2021 7 minutes ago, Newbie said: It surely depends upon which vaccine is being administered. Those receiving the Pfizer vaccine in the earlier groups should get there second dose as specified after 3 weeks, but for those getting the AZ vaccine, the latest evidence shows that giving the second dose after a longer interval provides greater protection, hence the advice from WHO, SAGE and from the CEO of Astra Zeneca who supported the UK approach for their vaccine. As far as the AZ vaccine is concerned, there is no logic in saying that we want to give the second dose as early as possible to those most at risk (i.e. after 4 weeks), because we want to give them maximum protection as quickly as possible, if the science shows that doing so doesn't give the maximum protection. Ultimately that strategy would leave the highest priority groups with lower levels of protection than the lower priority groups (assuming that the dosing schedule was changed for those groups as you suggested). Yes, but if you look at our vaccination stats, you will see that the majority have been given the Pfizer. I still maintain, the best approach is to get th best possible protection for the most vulnerable as soon as possible. Besides, as have said before, if the AZ vaccine really was that good, it would be a single dose vaccine. Quote Link to comment Share on other sites More sharing options...
Banker Posted February 12, 2021 Author Share Posted February 12, 2021 11 minutes ago, Newbie said: It surely depends upon which vaccine is being administered. Those receiving the Pfizer vaccine in the earlier groups should get there second dose as specified after 3 weeks, but for those getting the AZ vaccine, the latest evidence shows that giving the second dose after a longer interval provides greater protection, hence the advice from WHO, SAGE and from the CEO of Astra Zeneca who supported the UK approach for their vaccine. As far as the AZ vaccine is concerned, there is no logic in saying that we want to give the second dose as early as possible to those most at risk (i.e. after 4 weeks), because we want to give them maximum protection as quickly as possible, if the science shows that doing so doesn't give the maximum protection. Ultimately that strategy would leave the highest priority groups with lower levels of protection than the lower priority groups (assuming that the dosing schedule was changed for those groups as you suggested). When the question was asked today about times we just got a load of waffle from Henny which didn’t really answer the question Quote Link to comment Share on other sites More sharing options...
Newbie Posted February 12, 2021 Share Posted February 12, 2021 4 minutes ago, Cambon said: Yes, but if you look at our vaccination stats, you will see that the majority have been given the Pfizer. I still maintain, the best approach is to get th best possible protection for the most vulnerable as soon as possible. Besides, as have said before, if the AZ vaccine really was that good, it would be a single dose vaccine. That will probably change soon since the UK has ordered 100 million AZ vaccines and 40 million Pfizer ones. It should be possible to have different dosing schedules for different vaccines. They are different schedules anyway insofar as the Pfizer second dose is 3 weeks and the AZ second dose is currently 4 weeks Quote Link to comment Share on other sites More sharing options...
Newbie Posted February 12, 2021 Share Posted February 12, 2021 8 minutes ago, Cambon said: Besides, as have said before, if the AZ vaccine really was that good, it would be a single dose vaccine. No-one is proposing a single dose schedule for the AZ vaccine Quote Link to comment Share on other sites More sharing options...
madmanxpilot Posted February 12, 2021 Share Posted February 12, 2021 21 minutes ago, Newbie said: It surely depends upon which vaccine is being administered. Those receiving the Pfizer vaccine in the earlier groups should get there second dose as specified after 3 weeks, but for those getting the AZ vaccine, the latest evidence shows that giving the second dose after a longer interval provides greater protection, hence the advice from WHO, SAGE and from the CEO of Astra Zeneca who supported the UK approach for their vaccine. As far as the AZ vaccine is concerned, there is no logic in saying that we want to give the second dose as early as possible to those most at risk (i.e. after 4 weeks), because we want to give them maximum protection as quickly as possible, if the science shows that doing so doesn't give the maximum protection. Ultimately that strategy would leave the highest priority groups with lower levels of protection than the lower priority groups (assuming that the dosing schedule was changed for those groups as you suggested). Exactly on point. Quote Link to comment Share on other sites More sharing options...
madmanxpilot Posted February 12, 2021 Share Posted February 12, 2021 8 minutes ago, Banker said: When the question was asked today about times we just got a load of waffle from Henny which didn’t really answer the question She did say the dosing strategy was currently under review in light of the recent data. Quote Link to comment Share on other sites More sharing options...
Itsmeee Posted February 12, 2021 Share Posted February 12, 2021 (edited) I just wish our Health minister would learn how to pronounce Pfizer. It makes me wince every time he says ‘pfifezer’ Edited February 12, 2021 by Itsmeee 1 Quote Link to comment Share on other sites More sharing options...
yorik Posted February 12, 2021 Share Posted February 12, 2021 (edited) 1 hour ago, Itsmeee said: I just wish our Health minister would learn how to pronounce Pfizer. It makes me wince every time he says ‘pfifezer’ Probably thinks it’s Aldi brand Tizer Edited February 12, 2021 by yorik Bloody autocorrect 2 Quote Link to comment Share on other sites More sharing options...
Kopek Posted February 12, 2021 Share Posted February 12, 2021 If it's German, should be pron. Fight-zer, unless it's a family name? David doesn't do 'foreign', not even Manx! Amuses me that Henri E repeats DA and HQs pron, as if, not to embarrass them???? 1 Quote Link to comment Share on other sites More sharing options...
madmanxpilot Posted February 12, 2021 Share Posted February 12, 2021 Israeli vaccine rollout data. Impressive. 1 Quote Link to comment Share on other sites More sharing options...
Happier diner Posted February 13, 2021 Share Posted February 13, 2021 11 hours ago, madmanxpilot said: Israeli vaccine rollout data. Impressive. That's very impressive 1 Quote Link to comment Share on other sites More sharing options...
Barlow Posted February 15, 2021 Share Posted February 15, 2021 I'm going, if only to see the super refurb work and the smell of fresh paint: Quote Link to comment Share on other sites More sharing options...
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